hydroxychloroquine works

35,497 Views | 210 Replies | Last: 3 yr ago by BearForce2
chazzed
How long do you want to ignore this user?
To quote a recent post by janky1, "LOL":

https://www.readfrontier.org/stories/oklahoma-trying-to-return-its-2m-stockpile-of-hydroxychloroquine/
BearForce2
How long do you want to ignore this user?
chazzed said:

To quote a recent post by janky1, "LOL":

https://www.readfrontier.org/stories/oklahoma-trying-to-return-its-2m-stockpile-of-hydroxychloroquine/

If you were dying and there was no vaccine, you'd take it, don't lie.
The difference between a right wing conspiracy and the truth is about 20 months.
hanky1
How long do you want to ignore this user?
Here we go

Unit2Sucks
How long do you want to ignore this user?
hanky1 said:

Here we go


Please link the preprint study so we can review. I know you enjoy your premature victory lap but it's fair to actually show your work. There have been numerous conflicting studies on HCQ/AZM impact on COVID, so we can't rely on a random tweet from a RWNJ twitter account.
bearister
How long do you want to ignore this user?
I hope the unvaxed fat f@ucks in the South gobble it like mints when they get the variant from India.
Cancel my subscription to the Resurrection
Send my credentials to the House of Detention

β€œI love Cal deeply. What are the directions to The Portal from Sproul Plaza?”
BearForce2
How long do you want to ignore this user?
Unit2Sucks said:

hanky1 said:

Here we go


Please link the preprint study so we can review. I know you enjoy your premature victory lap but it's fair to actually show your work. There have been numerous conflicting studies on HCQ/AZM impact on COVID, so we can't rely on a random tweet from a RWNJ twitter account.

You can find your own links, this hasn't been a good month or year for "science", media, or truth.
The difference between a right wing conspiracy and the truth is about 20 months.
B.A. Bearacus
How long do you want to ignore this user?
hanky1 said:

Here we go


How many Breaking911 citations did hanky1 include in his PhD dissertation?

MinotStateBeav
How long do you want to ignore this user?
BearForce2 said:

Unit2Sucks said:

hanky1 said:

Here we go


Please link the preprint study so we can review. I know you enjoy your premature victory lap but it's fair to actually show your work. There have been numerous conflicting studies on HCQ/AZM impact on COVID, so we can't rely on a random tweet from a RWNJ twitter account.

You can find your own links, this hasn't been a good month or year for "science", media, or truth.
Trump was right again, and the democrats and their PR machine media are responsible for the dead.
MinotStateBeav
How long do you want to ignore this user?
bearister said:

I hope the unvaxed fat f@ucks in the South gobble it like mints when they get the variant from India.

You do realize some people actually HAD covid, they don't need the vaccine, they have the antibodies. I almost took the vax, but I am 100% certain I had it in March of 2020, It totally screwed up my taste buds, still to this day.
bearister
How long do you want to ignore this user?
MinotStateBeav said:

bearister said:

I hope the unvaxed fat f@ucks in the South gobble it like mints when they get the variant from India.

You do realize some people actually HAD covid, they don't need the vaccine, they have the antibodies. I almost took the vax, but I am 100% certain I had it in March of 2020, It totally screwed up my taste buds, still to this day.



" It's much better to get yourself vaccinated. Then you don't have to worry moving forward until we learn more about whether we need booster shots or not," Dr. Englund clarifies."

When Should You Get Vaccinated if You've Had COVID-19? Health Essentials from Cleveland Clinic


https://health.clevelandclinic.org/when-should-you-get-vaccinated-if-youve-had-covid-19/
https://www.google.com/amp/s/health.clevelandclinic.org/when-should-you-get-vaccinated-if-youve-had-covid-19/amp/


Should I Get The Vaccine If I Had COVID? : Goats and Soda : NPR


https://www.npr.org/sections/goatsandsoda/2021/05/21/998639795/coronavirus-faq-i-had-covid-should-i-get-the-vaccine

Do I still need to get vaccinated if I've already had COVID-19? - Mayo Clinic


https://www.mayoclinic.org/do-i-still-need-to-get-vaccinated-if-ive-already-had-covid-19/vid-20507033


*My wife and I believe we had Covid in February /March 2020 time frame (although Cal88 poo pooed that) but we got vaxed in March 2021 anyway. Better safe than sorry.


**Isn't St. Barnabas Medical Center in New Jersey where tRump got his taint transplant?
Cancel my subscription to the Resurrection
Send my credentials to the House of Detention

β€œI love Cal deeply. What are the directions to The Portal from Sproul Plaza?”
dajo9
How long do you want to ignore this user?
MinotStateBeav said:

BearForce2 said:

Unit2Sucks said:

hanky1 said:

Here we go


Please link the preprint study so we can review. I know you enjoy your premature victory lap but it's fair to actually show your work. There have been numerous conflicting studies on HCQ/AZM impact on COVID, so we can't rely on a random tweet from a RWNJ twitter account.

You can find your own links, this hasn't been a good month or year for "science", media, or truth.
Trump was right again, and the democrats and their PR machine media are responsible for the dead.


Oh? Can you tell me when Trump took hydroxychloroquine and how it helped him?
hanky1
How long do you want to ignore this user?
B.A. Bearacus said:

hanky1 said:

Here we go


How many Breaking911 citations did hanky1 include in his PhD dissertation?




This is perfectly normal procedure in this particular industry to publish preprints before the article. What's your point?
AunBear89
How long do you want to ignore this user?
I think his point is that you are not as smart as you think you are.
"There are three kinds of lies: lies, damned lies, and statistics." -- (maybe) Benjamin Disraeli, popularized by Mark Twain
Unit2Sucks
How long do you want to ignore this user?
Here's the paper. Not surprised some RWNJ twitter account oversimplified the results.

Quote:

Abstract
Introduction This observational study looked at 255 COVID19 patients who required invasive mechanical ventilation (IMV) during the first two months of the US pandemic. Through comprehensive, longitudinal evaluation and new consideration of all the data, we were able to better describe and understand factors affecting outcome after intubation.
Methods All vital signs, laboratory values, and medication administrations (time, date, dose, and route) were collected and organized. Further, each patient's prior medical records, including PBM data and available ECG, were reviewed by a physician. These data were incorporated into time-series database for statistical analysis.
Results By discharge or Day 90, 78.2% of the cohort expired. The most common pre-existing conditions were hypertension, (63.5%), diabetes (59.2%) and obesity (50.4%). Age correlated with death. Comorbidities and clinical status on presentation were not predictive of outcome. Admission markers of inflammation were universally elevated (>96%). The cohort's weight range was nearly 7-fold. Causal modeling establishes that weight-adjusted HCQ and AZM therapy improves survival by over 100%. QTc prolongation did not correlate with cumulative HCQ dose or HCQ serum levels.
Discussion This detailed approach gives us better understanding of risk factors, prognostic indicators, and outcomes of Covid patients needing IMV. Few variables were related to outcome. By considering more factors and using new methods, we found that when increased doses of co-administered HCQ and AZM were associated with >100% increase in survival. Comparison of absolute with weight-adjusted cumulative doses proves administration 80 mg/kg of HCQ with > 1 gm AZM increases survival in IMV-requiring Covid patients by over 100%. According to our data, HCQ is not associated with prolongation. Studies, which reported QTc prolongation secondary to HCQ, need to be re-evaluated more stringently and with controls.
The weight ranges of Covid patient cohorts are substantially greater than those of most antibiotic RCTs. Future clinical trials need to consider the weight variance of hospitalized Covid patients and need to study therapeutics more thoughtfully.
Comment by one of the authors:
Quote:

First, the cumulative was not, for most pts, a measure of length of stay or determined by death. The most commonly used cumulative dose of HCQ = 2,400 mg. This dose/regimen was recommended, as noted in the paper by Yao et al., based upon computer modeling. The 2,400 mg dose was given over 5 days, 800 mg on Day and 400 mg on Days 2-5. The treating or consulting ID physician chose the cumulative dose.

In late March, the French data came out and some switched to the French regimen, 600 mg of HCQ x 10 days plus azithromycin x 5 days. Most pts received the 800 mg first day dose, which was started by the ER docs and was a click in the computer ordering system. The ID docs saw the pt the next morning. Many continued the pt on 400 mg per day for 4 more days. Others switched to 600 mg per day. So, by Day 5 on the latter regimen, the cumulative HCQ dose = 3,200 mg or > 3 gm or the cut-off used in our paper. In other words, it took just as long to get to > 3 gm and as it took to get to 2,400 mg.

In a simplistic way to control for length of stay (LOS), we analyzed the effect of >3gHCQ/ >1gAZM on outcome after removing those patients, who had a LOS <= 5 days. All 49 patients with a LOS <= 5 days expired; none took > 3,000 mg HCQ and > 1,000 mg AZM.

The 169 remaining patients serve as the "untreated" group and had a survival rate = 21.3%. The >3gHCQ />1gAZM group's survival rate = 48.6%. This difference = 27.3%, which is still large and highly statistically significant (difference = 27.3%; 95% C.I. = 10.1-43.7%; p = 0.0006).
In other words, even after eliminating all patients who had a LOS <= 5 days from the "untreated" group, the survival rate of the HCQ/AZM was more than 2.2-fold that of the "untreated" group. BTW, this type of analysis is heavily biased against showing a difference between treatment with HCQ, because the treatment may have an effect before Day 5.

Remember, most of the "untreated" group did receive HCQ, just <= 3 gm.
In other words, cumulative dose of HCQ was not a marker of survival. The cumulative HCQ dose was determined by the ID doctor seeing the pt. Different ID doctors interpreted the available data on HCQ differently. Essentially, they chose between the 2,400 mg without AZM or the 6,000 mg total HCQ dose with AZM or no HCQ at all. A few ID doctors split the middle and used ~3 gm of HCQ with AZM.
Many ID doctors did not use AZM with HCQ for fear or concern about prolonging the QTc interval on the ECG. We, instead, followed the QTc interval closely.
Weight-based HCQ cumulative dose was more strongly associated with survival and absolute cumulative dose. This fact essentially rules out HCQ cumulative dose being a marker of survival as well.
Lighter pts reached a weight-based cumulative HCQ dose well before heavier pts. If a pt weighed 50% of another pt, it took 50% of the days to reach a given weight-based HCQ cumulative dose.
These pts typically received 800 mg HCQ on Day 1 and then 600 mg per day.
A 60 kg pt reached 40 mg/kg by Day 4, while a 120 kg pt, didn't reach 40 mg/kg until Day 8.
SMS

We have heard so many claims about HCQ over the past 15 months that it's hard to say that any clarity has emerged as to what HCQ advocates are actually saying. This small study is different from what Cal88 swore up and down was the proper approach. Cal88 told us that you have to use HCQ early and often and that if you wait until people are ventilated it's too late. This study only involved ventilated people. Also this study was done early in the pandemic before we developed better treatments for hospitalized patients like dexamethosone among other things.

Dexamethosone was probably the drug that did more than anything else to reduce the death rate of hospitalized patients but it never became politicized because it actually worked.
BearForce2
How long do you want to ignore this user?
AunBear89 said:

I think his point is that you are not as smart as you think you are.
And no one here is doubting your intelligence.
The difference between a right wing conspiracy and the truth is about 20 months.
AunBear89
How long do you want to ignore this user?
BearForce2 said:

AunBear89 said:

I think his point is that you are not as smart as you think you are.
And no one here is doubting your intelligence.


Pssst. I have little to no regard for the opinions of morons like you.

But thanks for sharing. You better check your Twitter feed so you can find out what your next thought is supposed to be.
"There are three kinds of lies: lies, damned lies, and statistics." -- (maybe) Benjamin Disraeli, popularized by Mark Twain
Big C
How long do you want to ignore this user?

Now that we know Hydroxychloroquine is indeed actually a wonder drug and now that we know that the area outside the White House wasn't cleared so that Trump could walk out and hold up the Bible and now that we know that the patriotic Capitol protests on 1/6 do not merit further investigation, I have one question:

When's that Reinstatement, baby? It will have the largest crowd EVER to attend a Presidential Reinstatement!!!
BearForce2
How long do you want to ignore this user?
Big C said:


Now that we know Hydroxychloroquine is indeed actually a wonder drug and now that we know that the area outside the White House wasn't cleared so that Trump could walk out and hold up the Bible and now that we know that the patriotic Capitol protests on 1/6 do not merit further investigation, I have one question:

When's that Reinstatement, baby? It will have the largest crowd EVER to attend a Presidential Reinstatement!!!

Instead, what if we gather the media and Biden supporters at the Capitol and serve crow and humble pie? For desert, Biden's and Nancy's favorite ice cream with assorted nut toppings, lots of nuts. All you can eat.
The difference between a right wing conspiracy and the truth is about 20 months.
Big C
How long do you want to ignore this user?

Can we work in fruits somewhere, to go with the nuts? When visiting in-laws and family in Florida and West Virginia, respectively, I always told them I'm from the land of fruits and nuts before they got a chance to say it. Sort of a preemptive defensive strike. Then we proceeded to get along fine.
dajo9
How long do you want to ignore this user?
Big C said:


Can we work in fruits somewhere? When visiting in-laws and family in Florida and West Virginia, respectively, I always told them I'm from the land of fruits and nuts before they got a chance to say it. Preemptive strike. Then we proceeded to get along fine.


I didn't get along with my Missouri relatives. I don't preemptively surrender. I asked them why they were talking nonsense.
Big C
How long do you want to ignore this user?
dajo9 said:

Big C said:


Can we work in fruits somewhere? When visiting in-laws and family in Florida and West Virginia, respectively, I always told them I'm from the land of fruits and nuts before they got a chance to say it. Preemptive strike. Then we proceeded to get along fine.


I didn't get along with my Missouri relatives. I don't preemptively surrender. I asked them why they were talking nonsense.

How did they explain their talking nonsense?

In these types of situations, I feel like non-engagement is totally different than surrender. Better to have a few laughs and not talk politics. If some of my (distant) right-wing family members really want to debate things with me, fine, we can do that, and I will eviscerate them. Problem is, they won't admit defeat, even to themselves. And then life goes on...
dajo9
How long do you want to ignore this user?
Big C said:

dajo9 said:

Big C said:


Can we work in fruits somewhere? When visiting in-laws and family in Florida and West Virginia, respectively, I always told them I'm from the land of fruits and nuts before they got a chance to say it. Preemptive strike. Then we proceeded to get along fine.


I didn't get along with my Missouri relatives. I don't preemptively surrender. I asked them why they were talking nonsense.

How did they explain their talking nonsense?

In these types of situations, I feel like non-engagement is totally different than surrender. Better to have a few laughs and not talk politics. If some of my (distant) right-wing family members really want to debate things with me, fine, we can do that, and I will eviscerate them. Problem is, they won't admit defeat, even to themselves. And then life goes on...


They said they thought it was funny
BearForce2
How long do you want to ignore this user?


They also won a Pulitzer for their coverage of the Russia hoax.

Quote:

Pulitzer is the prize for most believable propaganda.
The difference between a right wing conspiracy and the truth is about 20 months.
dajo9
How long do you want to ignore this user?
Bearforce2 is relentless in his attacks on the media because his political side is so stupid, corrupt, dishonest, and incompetent. Attacking the messenger is all they've got.
BearForce2
How long do you want to ignore this user?
dajo9 said:

Bearforce2 is relentless in his attacks on the media because his political side is so stupid, corrupt, dishonest, and incompetent. Attacking the messenger is all they've got.


You spent the last 4+ years believing lies that you wanted to believe. That's called delusion.
The difference between a right wing conspiracy and the truth is about 20 months.
dajo9
How long do you want to ignore this user?
BearForce2 said:

dajo9 said:

Bearforce2 is relentless in his attacks on the media because his political side is so stupid, corrupt, dishonest, and incompetent. Attacking the messenger is all they've got.


You spent the last 4+ years believing lies that you wanted to believe. That's called delusion.


That was like every week during the Trump Administration
BearForce2
How long do you want to ignore this user?
dajo9 said:

BearForce2 said:

dajo9 said:

Bearforce2 is relentless in his attacks on the media because his political side is so stupid, corrupt, dishonest, and incompetent. Attacking the messenger is all they've got.


You spent the last 4+ years believing lies that you wanted to believe. That's called delusion.


That was like every week during the Trump Administration

I know.
The difference between a right wing conspiracy and the truth is about 20 months.
BearForce2
How long do you want to ignore this user?
https://news.yahoo.com/study-shows-hydroxychloroquine-zinc-treatments-210300816.html




I wonder how many lives could have been saved if it weren't for left wing nutjobs spreading disinformation?

The difference between a right wing conspiracy and the truth is about 20 months.
BearForce2
How long do you want to ignore this user?
Quote:

A new study shows that the controversial drug hydroxychloroquine touted by former President Donald Trump increased the survival rate of severely ill coronavirus patients.

I like how the yahoos are referring to a drug that has been around for a long time as "controversial".
The difference between a right wing conspiracy and the truth is about 20 months.
Unit2Sucks
How long do you want to ignore this user?
hanky1 said:

Here we go


LOL the fake news tweet was deleted and hanky's legacy of failure continues.
hanky1
How long do you want to ignore this user?


Give it a little more time.

hanky1 will have the last laugh
B.A. Bearacus
How long do you want to ignore this user?
hanky1 said:



Give it a little more time.

hanky1 will have the last laugh

You undoubtedly will be laughed at last. Last is a fitting culmination of throughout and all along the way.

BearForce2
How long do you want to ignore this user?
The difference between a right wing conspiracy and the truth is about 20 months.
Unit2Sucks
How long do you want to ignore this user?
B.A. Bearacus said:

hanky1 said:



Give it a little more time.

hanky1 will have the last laugh

You undoubtedly will be laughed at last. Last is a fitting culmination of throughout and all along the way.


Oops.

This is peak Hanky - even his own sources are admitting they are wrong within hours of him falling for their scams.
oski003
How long do you want to ignore this user?
Outside of masks, sanitizer, hand washing, social distancing, and "the vaccine," what else does the NIH recommend for prevention of Covid 19?

How about if you test positive with mild symptoms, such as only a fever?
 
×
subscribe Verify your student status
See Subscription Benefits
Trial only available to users who have never subscribed or participated in a previous trial.