I'd be cautious with that article. There are definitely some true things in there, but there's a lot of misinformation mixed in. The biggest problem is that the author is confused about the vertical set vs. the 2-point stance. We're in a 2-point stance every play, but we absolutely do not use the vertical set on run plays. Just watch video of one run play and one drop-back pass play and it's easy to tell the difference.
As for the lining up in a V thing, this is what every team does. Here's a picture of the Giants:
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The Chiefs:
?w=650&h=365&q=85 Here's us:

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The Chiefs picture has the biggest stagger of the bunch, and their guards are the only ones in a 3-point stance. The V is totally irrelevant to the points she's making.
Also, in lots of dropback pass protections the OL's first steps will be backwards. The question is, how far do they drop back before anchoring? Also, we don't vertical set on every dropback pass. Our entire dropback play-action game, which we use more than you might think for a spread team, uses a slide protection with an OG pulling away from the slide, making the protection look like a power run (in the technical sense of "power" mentioned by MisterNoodle, not the broad sense of "anything where there are lots of big guys right up the middle").
The author also talks a lot about OL splits. That has nothing to do with the vertical set. She seems to be confusing the vertical set with Mike Leach's general philosophy on taking wide splits in order to turn the whole OL vs. DL into a series of 1-on-1's. We don't take splits like Leach teams. Also, in just about every case the DL can't just rush whatever gap they want, because then the defense isn't sound and they're risking the QB breaking contain and buying more time to throw. Wide splits might make it easier to execute called stunts, but that's a different issue. And anyway, like I said, we don't use Leach-like splits.
She mentions that screens run a higher risk of being picked by DL in the vertical set. Most of our screens come on run/pass packaged plays, where the OL is legitimately run blocking. As for jailbreak screens, how many of those have been picked off in the last two seasons?
There's also a gentle assumption throughout the article that our offense will be stopped by the same things that stop Oregon's offense for schematic reasons. Not true.
On one note unrelated to the article, lots of times people think that more blockers = better blocking. This is only true in a limited sense. If the D only rushes three or four, then obviously 8 blockers is better than 5. Once the D starts blitzing and the offense starts releasing more than two receivers into routes, though, it gets blurry. If the offense splits out a third or fourth WR, then the defense will almost always remove a guy from the box to cover him. When you take blockers out of the core of the formation, you're really just turning an 8-on-7 into a 7-on-6 or a 6-on-5. If the offense is capable at running 4-verticals (something you can't run out of the I), then they can force the defense into Cover-2. If the offense is 4-wide then, the numbers shake out like this: 2 safeties deep + 2 CB's plus 2 OLB's/NB's lined up over the inside WR's = 5 defenders left in the box to blitz 5 blockers. If the offense were an I-formation team instead, then the defense would be more inclined to play Cover-3 or Cover-1, which changes the math: 1 safety + 2 CB's = 8 defenders left in the box to rush the passer against 7-blockers (only 8 if the offense goes absolute max protect, but then they only have two WR's in the route, making it harder to spring guys open).
The big advantage of the spread is that, even if the defense can still technically outnumber you, the fewer players you have in the box the easier it is to sort out your assignments against blitzes. If you're an I-formation team, then your max protect will have 8 blockers. If the defense has an 8-man box, then you're 8-vs.-8, which looks the same as 5-on-5 or 6-on-6, but there's a huge difference. Most blitzes only use five pass rushers. If the defense has 8 men in the box against the I-formation, then they will rush 4 DL, and then the fifth rusher can be any one of the four remaining box defenders, giving the offense a 25% chance of knowing who the extra rusher is. Spread offenses will often be outnumbered 6-on-5 in the box, but it's not actually that bad. Assuming again that four of the pass rushers will be the DL, there are only two players left in the box to blitz. The OL picks one of them to block, and the QB throws hot if the other blitzes, and boom, all potential rushers are accounted for without anyone having to think too hard. Even still, most 5-man protections come in the quick game. If we're dropping back or going play-action, the RB is usually check-releasing, so for most of our drop-back game we're actually in a 6-man protection as it is.