Unit2Sucks said:
oski003 said:
Pfizer data for Israel in July shows that Pfizer was only 16% effective against symptomatic infection for those vaccinated in January (at 6 months).
Since preventing infection appears to be a failure, hopefully the U.S. will support alternative vaccines with safer profiles that will still prevent hospitalization and death.
Some, such as INO 4800 which the U.S. defunded due to pfizers success, have superior cellular immunity and little to no side effects.
Inovio is just about to start phase 3 trials so it's too soon to claim that it has superior safety and efficacy. It is also unlikely to convince any anti-vaxxers to change their position - it's still a DNA vaccine and they will claim it's turning us into robots or whatever.
I welcome all safe and effective vaccines and hope we can add Inovio and others to our arsenal. As others have said, we need people to get vaccinated to control the pandemic. I don't think anyone here (besides you) has religion on what those vaccines are.
Quote:
"The real problem in this country is not that we need to boost the vaccinated - it's that we need to vaccinate the unvaccinated," Offit said. "That's the problem. Until we do that, we're going to suffer in this country."
Moore put it even more starkly: "There are 100,000 to 200,000 people walking around America today who will be dead by the end of the year, and mostly self-inflicted, by refusing vaccination," he said. "That's the bigger issue."
source
Pfizer (Gottlieb) and Moderna (Hahn and Fauci) made sure that non-BP vaccines were not given an opportunity to run a P3 in the USA.
The FDA put a hold on Inovio's P3 trial the week before it was to start. The FDA has not lifted the hold a year later and Inovio changed their strategy to a worldwide approach about 3 months ago. The Department of Defense was going to fund their P3 but cancelled due the impossibility of running a USA P3 with EUA vaccines available. They are finally about to start in Brazil, Czech, China, Mexico, and other places.
Inovio only has data on about 1000 people but the efficacy is strong and the cellular responses are better than the mRNA vaccines. I know about a dozen people in the trial. Some are doctors, nurses, and pharmacists.
The humoral response is not so strong, which is what the Moderna led OWS and Fauci have focused on. The safety data from Inovio's P1 and P2 is like a flu shot, unlike mRNA, which leads the league in side effects.
Yes, Inovio is a DNA tech. So is JnJ. Did you know that? Well, you learn something everyday. The government is fraudulently marketing JnJ as a traditional vaccine. Instead, they should be advancing DNA tech. Inovio's delivery method, although different, is safer that JnJ's, based on p1 and P2 trials.
Edited to add three things:
1) Generally, cellular immunity is what prevents severe disease while humoral immunity prevents infection;
2) I am a HUGE fan of vaccines that don't cause myocarditis; and
3) I do not know whether or not Inovio causes myocarditis. All I know is that mRNA does at an alarming rate and had a WAY WORSE safety profile in P1 and P2 than Inovio.